新“流感神药”爆火！医生提醒
<section style="text-align: center;margin-bottom: 16px;" data-mpa-powered-by="yiban.io"></section><p></p><section data-role="outer" label="edit by 135editor"><section data-role="outer" label="edit by 135editor"><section data-role="outer" label="edit by 135editor"><section style="text-align: center;line-height: 1.75em;"><span style="font-size: 16px;color: rgb(61, 170, 214);"><strong><span style="caret-color: red;">进入流感季后</span></strong></span></section><section style="text-align: center;line-height: 1.75em;"><span style="font-size: 16px;color: rgb(61, 170, 214);"><strong><span style="caret-color: red;">流感用药需求量大幅增长</span></strong></span></section><section style="text-align: center;line-height: 1.75em;"><span style="font-size: 16px;color: rgb(61, 170, 214);"><strong><span style="caret-color: red;">玛巴洛沙韦片</span></strong></span></section><section style="text-align: center;line-height: 1.75em;"><span style="font-size: 16px;color: rgb(61, 170, 214);"><strong><span style="caret-color: red;">成为继奥司他韦后的</span></strong></span></section><section style="text-align: center;line-height: 1.75em;"><span style="font-size: 16px;color: rgb(61, 170, 214);"><strong><span style="caret-color: red;">“网红”流感用药</span></strong></span></section><p style="text-align:center;"><span style="color:#4f81bd;"><strong><span style="caret-color: red;"><br/></span></strong></span></p><p style="text-align: center;"></p><p style="line-height: 2em;margin-left: 8px;margin-right: 8px;"><span style="font-size: 16px;"><span style="caret-color: red;">据人民日报客户端17日援引红星新闻报道，查询多个公立医院药品公示价格注意到，</span><span style="font-size: 16px;color: rgb(61, 170, 214);"><strong><span style="color: rgb(61, 170, 214);caret-color: red;">一盒玛巴洛沙韦片（规格：20mg*2片）的售价为222.36元。而在网上购药平台，有药店标出418元/盒的价格，高出医院超87%，单片价格超200元。</span></strong></span><br/></span></p><p style="line-height: 2em;margin-left: 8px;margin-right: 8px;"><span style="font-size: 16px;">目前，进口玛巴洛沙韦已被纳入国家医保药品目录，上市许可持有人为罗氏制药。不过从2021年获批至今年3月，玛巴洛沙韦的适龄人群方才扩龄至5岁及以上患者。与奥司他韦不同的是，该药半衰期较长，全程只需一次服用。</span></p><p style="line-height: 2em;margin-left: 8px;margin-right: 8px;"><span style="font-size: 16px;">12月16日，河南省儿童医院南院区急诊科主任宋春兰提醒，<span style="color: rgb(61, 170, 214);"><strong>玛巴洛沙韦的适用患者群体存在限制性，对确诊流感的患者要求是年龄达五岁、体重在20公斤以上方可使用，并非普通感冒就可以使用。</strong></span></span></p><section data-tools="135编辑器" data-id="135690"><section style="margin: 10px auto;display: flex;justify-content: center;"><section style="transform: skew(-10deg);-webkit-transform: skew(-10deg);-moz-transform: skew(-10deg);-o-transform: skew(-10deg);"><section style="display: flex;justify-content: flex-end;"><section style="width: 25px;height: 25px;border-top: 3px solid rgb(159, 220, 252);border-right: 3px solid rgb(159, 220, 252);overflow: hidden;"><br/></section></section><section style="background-color: #ffffff;margin: -20px 5px;"><section style="background-color: #0060e8;"><p style="text-align:left;font-size: 16px;color: rgb(255, 255, 255);padding: 7px 18px;transform: skew(10deg);"><span style="font-size:17px;"><strong data-brushtype="text">有药店单盒售价超400元</strong></span></p><p style="text-align:left;font-size: 16px;color: rgb(255, 255, 255);padding: 7px 18px;transform: skew(10deg);"><span style="font-size:17px;"><strong data-brushtype="text">较医院售价高出87%</strong></span></p></section></section><section style="display: flex;justify-content: flex-start;"><section style="width: 25px;height: 25px;border-bottom: 3px solid rgb(159, 220, 252);border-left: 3px solid rgb(159, 220, 252);overflow: hidden;"><br/></section></section></section></section></section><section style="margin-left: 8px;margin-right: 8px;"><span style="font-size: 16px;">近日，流感肆虐之下，造就了新的“网红药”——玛巴洛沙韦。</span></section><p></p><p><span style="font-size: 15px;color: rgb(127, 127, 127);">截图自某电商平台</span></p><p style="line-height: 2em;margin-left: 8px;margin-right: 8px;"><span style="font-size: 16px;">鉴于该药使用方便、疗效明显，受到越来越多的患者关注。不过，单片价格高，也是玛巴洛沙韦的明显特征。</span></p><p style="line-height: 2em;margin-left: 8px;margin-right: 8px;"><span style="font-size: 16px;">目前，玛巴洛沙韦已被纳入国家医保药品目录，医保报销类别为医保乙类。查询多个公立医院药品公示价格注意到，一盒玛巴洛沙韦片（规格：20mg*2片）的售价为222.36元。</span></p><p></p><p><span style="font-size: 15px;color: rgb(127, 127, 127);">国家医保局官方微信公众号截图</span></p><p style="line-height: 2em;margin-left: 8px;margin-right: 8px;"><span style="font-size: 16px;">不过，玛巴洛沙韦价格在线上电商平台有不同程度上涨。多个网上购药平台显示，一盒玛巴洛沙韦片的价格大多都高于医院，标价300元左右的药店较多。其中有药店售价达418元/盒，高出医院超87%，单片价格超200元。</span></p><p></p><p style="line-height: 2em;margin-left: 8px;margin-right: 8px;"><span style="font-size: 16px;">从适用患者群体来看，<strong><span style="color: rgb(61, 170, 214);">该药在国内上市时间相对较短，部分年龄的临床试验数据缺乏，目前我国尚未批准用于流感预防及5岁以下患者的治疗。</span></strong>由于该药的半衰期较长，因此全程只需一次服用，使用较为方便。</span></p><p style="line-height: 2em;margin-left: 8px;margin-right: 8px;"><span style="font-size: 16px;">2021年，玛巴洛沙韦（商品名：速福达）在国内获批上市，上市许可持有人为罗氏制药(瑞士)公司。而公开资料显示，巴洛沙韦最早由日本药企盐野义开发，罗氏制药于2016年与日本药企盐野义达成合作共同开发玛巴洛沙韦市场。</span></p><p style="line-height: 2em;margin-left: 8px;margin-right: 8px;"><span style="font-size: 16px;">不过值得注意的是，此前速福达仅获批用于治疗12周岁及以上单纯性甲型和乙型流感患者。2023年3月21日，速福达扩龄，获批用于治疗既往健康的成人和5岁及以上儿童单纯性甲型和乙型流感患者，或存在流感相关并发症高风险的成人和12岁及以上儿童流感患者。</span></p><section data-tools="135编辑器" data-id="135690"><section style="margin: 10px auto;display: flex;justify-content: center;"><section style="transform: skew(-10deg);-webkit-transform: skew(-10deg);-moz-transform: skew(-10deg);-o-transform: skew(-10deg);"><section style="display: flex;justify-content: flex-end;"><section style="width: 25px;height: 25px;border-top: 3px solid rgb(159, 220, 252);border-right: 3px solid rgb(159, 220, 252);overflow: hidden;"><br/></section></section><section style="background-color: #ffffff;margin: -20px 5px;"><section style="background-color: #0060e8;"><p style="text-align:left;font-size: 16px;color: rgb(255, 255, 255);padding: 7px 18px;transform: skew(10deg);"><span style="font-size:17px;"><strong data-brushtype="text">医生：确诊患者需年龄达五岁</strong></span></p><p style="text-align:left;font-size: 16px;color: rgb(255, 255, 255);padding: 7px 18px;transform: skew(10deg);"><span style="font-size:17px;"><strong data-brushtype="text">体重在20公斤以上</strong></span></p></section></section><section style="display: flex;justify-content: flex-start;"><section style="width: 25px;height: 25px;border-bottom: 3px solid rgb(159, 220, 252);border-left: 3px solid rgb(159, 220, 252);overflow: hidden;"><br/></section></section></section></section></section><section style="line-height: 2em;"><span style="font-size: 16px;">12月16日，河南省儿童医院南院区急诊科主任宋春兰介绍，从医院目前的情况来看，的确有医生给合适的流感患儿开具玛巴洛沙韦口服。</span></section><section style="line-height: 2em;"><br/></section><section style="line-height: 2em;"><span style="font-size: 16px;">宋春兰表示，玛巴洛沙韦为流感病毒RNA聚合酶抑制剂，是一种新型抗流感病毒药物，<span style="font-size: 16px;color: rgb(61, 170, 214);"><strong>目前在我国已获批使用于5岁及以上确诊流感的患者，该药的适用患者群体存在限制性，并非普通感冒就可以使用。</strong></span></span></section><section style="line-height: 2em;"><br/></section><section style="line-height: 2em;"><span style="font-size: 16px;">“玛巴洛沙韦是确诊流感的大孩子吃的药，要求是年龄达五岁、体重在20公斤以上的患者方可使用。跟其他流感用药不同，玛巴洛沙韦全程只需要服用一次，有研究显示，可在24小时内停止流感病毒排毒，缩短流感传染期、安全性好，与其他抗流感药物相比，可快速缓解临床症状，停止病毒排毒，降低高危人群并发症，但在服用时，一定要关注临床适应症、用法用量、有无过敏反应等注意事项。”宋春兰说。</span></section><section style="line-height: 2em;"><br/></section><section style="line-height: 2em;"><span style="font-size: 16px;">另据扬子晚报报道，南京鼓楼医院药学部主任严思敏提醒，<span style="font-size: 16px;color: rgb(61, 170, 214);"><strong>孕</strong><strong>妇、重度肝功能不全、肾功能不全（肌酐清除率小于50 ml/min）的患者等特殊人群来说应尽量避免使用玛巴洛沙韦。</strong></span>即使是轻度的肝肾功能不全，也应当在专业医生的指导下使用。患者如果有在吃一些含有阳离子成分的药物，或者是一些含有铁剂、锌、钙、镁这类药物，以及需要用乳制品的人群，都要尽量避免与这类药物联用。</span></section><section powered-by="xiumi.us" style="margin-right: 8px;margin-bottom: 0px;margin-left: 8px;letter-spacing: 0.578px;text-wrap: wrap;line-height: 2em;"><section 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